ARUP's Laboratory Test Directory
| 0030191: B-Type Natriuretic Peptide |
![[ image for: Time Sensitive]](icon_1.jpg){kind=icon} | Time Sensitive |
| Test Mnemonic: BNP | |
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Methodology: Chemiluminescent Immunoassay
Performed: Sun-Sat Reported: Within 24 hours |
| Specimen Required: | |
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Collect: One 3 mL lavender (EDTA) or pink (K2EDTA).
Transport: 2 mL plasma, frozen. (Min: 0.5 mL) Submit specimen in an ARUP Standard Transport Tube. Remarks: If testing is not performed within four hours, separate plasma from cells and freeze. Separate plasma from cells ASAP. Unacceptable Conditions: Hemolyzed specimens collected in non-EDTA tubes. Specimens frozen in separator tube. Frozen whole blood. Specimen exposed to repeated freeze/thaw cycles. Ambient or refrigerated specimens. Stability: After separation from cells: Ambient: 4 hours; Refrigerated: 4 hours; Frozen: 4 months |
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| Reference Interval: |
| Refer to Interpretive Data. |
| Interpretive Data: | |
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A cutoff of 100 pg/mL has been demonstrated to provide the maximal combination of sensitivity, specificity, and negative predictive value for contributing to the diagnosis of congestive heart failure (CHF). A BNP value greater than or equal to 100 pg/mL is consistent with a diagnosis of CHF in the appropriate clinical setting. False-positive results are more common in females greater than 75 years of age. Blood concentrations of natriuretic peptides may also be elevated in patients with myocardial infarction and in patients who are candidates for or are undergoing renal dialysis.
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| CPT Code(s): | |
| 83880 |