ARUP's Laboratory Test Directory

Protein S, Functional : 0030114

Mnemonic: PROT S F

Methodology: Clotting
Performed: Sun-Sat
Reported: 1-2 days
Specimen Required: Collect:  One 5 mL lt. blue (sodium citrate).  Refer to the Hemostasis/Thrombosis Specimens section in the front of this User's Guide for specimen collection instructions.

Transport:  2 mL platelet-poor plasma, frozen. (Min: 1 mL) Submit specimen in an ARUP Standard Transport Tube.

Remarks:  CRITICAL FROZEN.  Separate specimens must be submitted when multiple tests are ordered.

Unacceptable Conditions:  Serum.  Nonfrozen or hemolyzed specimens.

Stability:  Ambient: 2 hours; Refrigerated: 4 hours; Frozen: 2 weeks
Reference Interval:
Male
1-89 days: 15-55%
90-179 days: 35-92%
180-364 days: 45-115%
1-5 years: 62-120%
6 years:  62-130%
7-9 years: 66-140%
10-11 years: 65-139%
12-13 years: 72-139%
14-15 years: 68-145%
16-17 years: 77-167%
18 years and older: 66-143%

Female
1-89 days: 15-55%
90-179 days: 35-92%
180-364 days: 45-115%
1-5 years: 62-120%
6 years:  62-130%
7-9 years: 62-151%
10-11 years: 65-142%
12-13 years: 70-140%
14-15 years: 55-145%
16-17 years: 51-147%
18 years and older: 57-131%
Interpretive Data: Patients on oral anticoagulants will have decreased functional protein C/S values. Patients should be off oral anticoagulant therapy for two weeks for accurate measurement of functional protein C/S levels.

Interfering factors: Artifactually decreased functional protein C/S values may be seen in patients with abnormally elevated levels of factor VIII. Artifactually elevated levels of functional protein C/S may be seen in patients receiving heparin therapy.
CPT Code(s): 85306
 
 

 

 

 
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