Reference Interval:
| Test Number
| Components
| Reference Interval
| | | Arsenic, Urine | 0-35.0 µg/L (based on Biological Exposure Index)
| | | Arsenic, Urine (24-hour) | 0-50.0 µg/d
| | | Arsenic per gram of creatinine | No reference interval (µg/g crt)
| | 0020734 | Arsenic, Fractionated, Urine
| | Test Number
| Components
| Reference Interval
| | | As Organic
| Refer to test 0020741 | | | Arsenic Total Inorganic
| Refer to test 0020737 | | | Arsenic, Methylated
| Refer to test 0020740 |
| | | Cadmium, Urine | 0.0-2.6 µg/L
| | | Cadmium, Urine (24-hour) | 0.0-3.3 µg/d
| | | Cadmium per gram of creatinine | 0.0-3.0 µg/g crt
| | | Copper, Urine | 0.2-8.0 µg/dL
| | | Copper, Urine (24-hour) | 3-50 µg/d
| | | Copper per gram of creatinine | No reference interval (µg/g crt)
| | | Lead, Urine | 0-23 µg/L
| | | Lead, Urine (24-hour) | 0-31 µg/d
| | | Lead per gram of creatinine | No reference interval (µg/g crt)
| | | Mercury, Urine | 0-10 µg/L
| | | Mercury, Urine (24-hour) | 0-15 µg/d
| | | Mercury per gram of creatinine | No reference interval (µg/g crt)
| | | Zinc, Urine | 15-120 µg/dL
| | | Zinc, Urine (24-hour) | 150-1200 µg/d
| | | Zinc per gram of creatinine | No reference interval (µg/g crt)
| | | Creatinine, Random
| No reference interval
| | 0020473 | Creatinine, 24-Hour Urine
| | Male
| Female
| 3-8 years: 140-700 mg/d
9-12 years: 300-1300 mg/d
13-17 years: 500-2300 mg/d
18-50 years: 1000-2500 mg/d
51-80 years: 800-2100 mg/d
81 years and older: 600-2000 mg/d
| 3-8 years: 140-700 mg/d
9-12 years: 300-1300 mg/d
13-17 years: 400-1600 mg/d
18-50 years: 700-1600 mg/d
51-80 years: 500-1400 mg/d
81 years and older: 400-1300 mg/d
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| Interpretive Data: |
Specific toxic thresholds for arsenic are not well defined. The ACGIH Biological Exposure Index is 35 µg/L for the sum of the inorganic and methylated forms of arsenic. For specimens with a total arsenic concentration between 35-2000 µg/L, fractionation is performed to determine the proportion of organic, inorganic, and methylated forms. If low-level chronic poisoning is suspected, the µg/gCRT ratio may be more sensitive than the total arsenic concentration. It may be appropriate to fractionate specimens with a µg/gCRT ratio greater than 30 µg/gCRT despite a total arsenic concentration less than 35µg/L; the laboratory will perform this on request.
The organic forms of arsenic, most commonly arsenobetaine, are considered nontoxic and arise primarily from food. Inorganic forms of arsenic, As(III) and As(V), are most toxic. Methylated forms (MMA and DMA) arise primarily from metabolism of inorganic forms but may also come from dietary sources and are of moderate toxic potential. As this test does not detect all species of arsenic, it is expected that the sum of the organic, inorganic, and methylated forms will not equal the total arsenic concentration.
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| CPT Code(s): |
82175 Arsenic; 82300 Cadmium; 82525 Copper; 83655 Lead; 83825 Mercury; 84630 Zinc; if reflexed, 82175 Arsenic fractionated
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