ARUP's Laboratory Test Directory
| 0025000: Arsenic, Urine with Reflex to Fractionated |
| Test Mnemonic: ARS U | |
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Methodology: Inductively Coupled Plasma/Mass Spectrometry/High Pressure Liquid Chromatography
Performed: Mon-Fri Reported: 1-5 days |
| Specimen Required: | |
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Collect: 24-hour or random urine collection. Specimen must be collected in a plastic container and should be refrigerated during collection. ARUP studies indicate that refrigeration of urine alone, during and after collection, preserves specimens as well as the preservatives mentioned, if tested within 8 days of collection.
Transport: 10 mL aliquot from a well-mixed collection at 2-8°C (Min: 5 mL). Submit specimen in two ARUP Trace Element-Free Transport Tubes (ARUP supply #43116). Pediatric Collection/Transport: 5 mL aliquot from a well-mixed collection at 2-8°C. Submit specimen in an ARUP Trace Element-Free Transport Tube (ARUP supply #43116). Remarks: Record total volume and collection time interval on transport tube and on test request form. Unacceptable Conditions: Urine collected within 48 hours after administration of a gadolinium (Gd) containing contrast media (may occur with MRI studies). Acid preserved urine. Stability: If the specimen is collected and stored in the appropriate container, the trace element values do not change with time. |
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| Interpretive Data: | |
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For specimens with a total arsenic concentration between 35-2000 ug/L, the proportion of organic, inorganic, and methylated forms is determined. The organic forms of arsenic, most commonly arsenobetaine, are considered nontoxic and arise primarily from food. Inorganic forms of arsenic [As(III) and As(V)] are most toxic. Methylated forms (MMA and DMA) arise primarily from metabolism of inorganic forms but may also come from dietary sources and are of moderate toxic potential. Specific toxic thresholds for arsenic are not well defined but the Biological Exposure Index established by ACGIH for the sum of the inorganic and methylated forms of arsenic is 35 ug/L. As this test does not detect all species of arsenic, it is expected that the sum of the organic, inorganic and methylated forms will not equal the total arsenic concentration.
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| CPT Code(s): | |
| 82175; if reflexed, add 82175 |