ARUP's Laboratory Test Directory

Electrolyte & Osmolality Profile, Fecal : 0020699

Mnemonic: FEC PRO

Methodology: Ion-Selective Electrode/Freezing Point Depression
Performed: Sun-Sat
Reported: Within 48 hours
Specimen Required: Collect:  24-hour or random liquid stool..

Transport:  10 g aliquot from well-mixed, 24-hour or random stool in a clean unpreserved stool transport vial (ARUP Supply #40910), frozen. (Min: 5 g)

Remarks:  CRITICAL FROZEN.   Stool must be liquid. Do not add saline or water to liquefy specimen. Indicate time and volume.

Unacceptable Conditions:  Formed stools.

Stability:  Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 1 month
Reference Interval:
 
Component Reference Interval
Sodium, Fecal Not Established
Potassium, Fecal Not Established
Magnesium, Fecal 0-110 mg/dL
Calculated Osmolality, Fecal By report
Osmolality, Fecal (measured) 0-16 years: 271-296 mOsm/kg
17 years and older: 280-303 mOsm/kg
Osmolal gap By report
  

Interpretive Data: Normal fecal fluid has an osmolality close to that of plasma (i.e., 290 mOsm/kg), a sodium concentration of about 30 mmol/L, a potassium concentration of about 75 mmol/L, and a magnesium concentration between 12 and 240 mg/dL (depending on diet) although it is usually less than 110 mg/dL. A fecal sodium  greater than 90 mmol/L and an osmolal gap less than 50 mOsm/kg suggests secretory diarrhea or osmotic diarrhea due to sodium-containing laxatives. A fecal sodium less than 60 mmol/L and an osmolal gap greater than 100 mOsm/kg suggests osmotic diarrhea. Fecal sodium greater than 150 mmol/L and osmolality greater than 400 mOsm/kg suggests contamination with concentrated urine. Fecal osmolality less than 250 mOsm/kg suggests contamination with hypoosmotic urine or water. 
CPT Code(s): 84999 Potassium; 84302 Sodium; 83735 Magnesium; 84999 Osmolality
 
 

 

 

 
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