ARUP's Laboratory Test Directory

Zinc Protoporphyrin (ZPP), Whole Blood Industrial : 0020614

Mnemonic: ZPP IND

Methodology: Quantitative Hematofluorometry
Performed: Mon-Fri
Reported: 1-4 days
Specimen Required: Collect: Lavender (EDTA), royal blue (EDTA), or tan (EDTA). Use royal blue (EDTA) tube when also testing for lead.

Specimen Preparation: Transport 1 mL whole blood. (Min: 0.2 mL)

Storage/Transport Temperature: Refrigerated.

Unacceptable Conditions: Specimens not collected in EDTA. Clotted, frozen, or hemolyzed specimens.

Stability (collection to initiation of testing): Ambient: 30 hours; Refrigerated: 5 weeks; Frozen: Unacceptable
Reference Interval:
 
Test Number Components Reference Interval
 Zinc Protoporphyrin (ZPP), Whole Blood 0-40 µg/dL
 Zinc Protoporphyrin (ZPP) to Heme Ratio 0-69 µmol ZPP/mol heme

Interpretive Data: For occupational exposure to lead, OSHA requires ZPP whole blood concentration to be reported in units of µg/dL. For adults, conversion of ZPP to units of µg/dL assumes a hematocrit of 45%.
Note: Elevated ZPP results are seen in early and late iron deficiency, the anemia of chronic disease, chronic lead poisoning, and erythropoietic protoporphyria.  Elevated bilirubin or riboflavin and hemolyzed, clotted, or improperly aliquoted specimens may falsely increase the ZPP concentration.
CPT Code(s): 84202
Cross References: Porphyrins (Zinc Protoporphyrin (ZPP), Whole Blood Industrial), Protoporphyrin (Zinc Protoporphyrin (ZPP), Whole Blood Industrial), ZPP (Zinc Protoporphyrin (ZPP), Whole Blood Industrial)