ARUP's Laboratory Test Directory

0020605: Zinc Protoporphyrin (ZPP), Whole Blood

Test Mnemonic: ZPP
Methodology: Hematofluorometry

Performed: Mon-Fri

Reported: 1-4 days

Specimen Required:  
Collect: One 7 mL royal blue or tan (EDTA) or one 5 mL lavender (EDTA) or pink (K2 EDTA).

Transport: 1 mL whole blood at 2-8°C. (Min: 0.5 mL)

Pediatric Collection/Transport: 0.2 mL whole blood at 2-8°C.

Remarks: Use royal blue (EDTA) tube when also testing for lead.  Protect from light during collection, storage, and shipment.

Unacceptable Conditions: Frozen, hemolyzed, or clotted samples.

Stability: Ambient: 30 hours; Refrigerated: 5 weeks; Frozen: Unacceptable

Reference Interval:
0-69 µmol ZPP/mol heme

Note:
Elevated ZPP results are seen in early and late iron deficiency, the anemia of chronic disease, chronic lead poisoning, and erythropoietic protoporphyria.  Elevated bilirubin or riboflavin and hemolyzed, clotted, or improperly aliquoted specimens may falsely increase the ZPP concentration.


A more specific test for free protoporphyrin is Porphyrins, Serum Total (0080429).  Erythrocyte Porphyrin (EP), Whole Blood (0020610), measures free protoporphyrin and zinc protoporphyrin.

CPT Code(s):
84202

 

 

 
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