Maternal Serum Screening

Maternal serum screening tests help identify pregnancies at increased risk for Down syndrome, trisomy 18, or open neural tube defects such as spina bifida. These tests have traditionally been performed in the second trimester and measure the levels of specific protein markers in maternal blood. Newer tests now combine first-trimester fetal ultrasound measurements along with measurements of biochemical markers in maternal blood to predict risk. ARUP offers second-trimester as well as first-trimester, integrated, and sequential screens.

Please click on the test code or test name to obtain a link to the Patient History Form for the desired test.

* Sonographer providing NT measurement must be certified by NTQR (SMFM) or FMF. Please contact a genetic counselor at (800) 242-2787 x2141 prior to sending first sample to ensure acceptability.

Patient Information

Test # Test Name Additional Information Test Keywords
0081293 Maternal Screening, Sequential, Specimen #1 Combined First- and Second-Trimester Screening MS SEQ-1, Prenatal Screening, nuchal translucency, NT, PN screen, Down, Downs, Down's, Trisomy 21, Trisomy 18, PAPP-A, two part screen, first trimester
0081294 Maternal Screening, Sequential, Specimen #2 Additional Technical Information Combined First- and Second-Trimester Screening MS SEQ-2, Prenatal Screening, nuchal translucency, NT, PN screen, Down, Downs, Down's, Trisomy 21, Trisomy 18, NTD, neural tube defects, two part screen, second trimester
0081062 Maternal Serum Screening, Integrated, Specimen #1 Additional Technical Information Combined First- and Second-Trimester Screening MS INT-1, Prenatal Screening, nuchal translucency, NT, PN screen, Down, Downs, Down's, Trisomy 21, Trisomy 18, PAPP-A, two part screen, first trimester
0081064 Maternal Serum Screening, Integrated, Specimen #2 Additional Technical Information Combined First- and Second-Trimester Screening MS INT-2, Prenatal Screening, nuchal translucency, NT, PN screen, Down, Downs, Down's, Trisomy 21, Trisomy 18, NTD, neural tube defects, two part screen, second trimester
0081150 Maternal Serum Screen, First Trimester Additional Technical Information First-Trimester Screening MS FT, Prenatal Screening, nuchal translucency, NT, PN screen, Down, Downs, Down's, Trisomy 21, Trisomy 18, PAPP-A, hCG
0081150 Maternal Serum Screen, First Trimester Additional Technical Information Maternal Serum Screening MS FT, Prenatal Screening, nuchal translucency, NT, PN screen, Down, Downs, Down's, Trisomy 21, Trisomy 18, PAPP-A, hCG
0081293 Maternal Screening, Sequential, Specimen #1 Maternal Serum Screening MS SEQ-1, Prenatal Screening, nuchal translucency, NT, PN screen, Down, Downs, Down's, Trisomy 21, Trisomy 18, PAPP-A, two part screen, first trimester
0081294 Maternal Screening, Sequential, Specimen #2 Additional Technical Information Maternal Serum Screening MS SEQ-2, Prenatal Screening, nuchal translucency, NT, PN screen, Down, Downs, Down's, Trisomy 21, Trisomy 18, NTD, neural tube defects, two part screen, second trimester
0081062 Maternal Serum Screening, Integrated, Specimen #1 Additional Technical Information Maternal Serum Screening MS INT-1, Prenatal Screening, nuchal translucency, NT, PN screen, Down, Downs, Down's, Trisomy 21, Trisomy 18, PAPP-A, two part screen, first trimester
0081064 Maternal Serum Screening, Integrated, Specimen #2 Additional Technical Information Maternal Serum Screening MS INT-2, Prenatal Screening, nuchal translucency, NT, PN screen, Down, Downs, Down's, Trisomy 21, Trisomy 18, NTD, neural tube defects, two part screen, second trimester
0080269 Quad Screen Alpha Fetoprotein, hCG, Estriol, and Inhibin A Maternal Serum Screening AFP MS4, Prenatal Screening, nuchal translucency, NT, PN screen, Down, Downs, Down's, Trisomy 21, Trisomy 18, NTD, neural tube defects, two part screen, second trimester
0080434 Maternal Serum Screen, Alpha Fetoprotein (Only) Maternal Serum Screening MS ONLY, Prenatal Screening, NTD, neural tube defects, second trimester
2007537 Non-Invasive Prenatal Testing for Fetal Aneuploidy Non-Invasive Prenatal Testing (Cell-Free DNA) NIPT ANEU, Panorama, NIPD, Natera, Ariosa, Sequenom, Harmony, Verinata, Maternity 21, MaterniT21, Verifi, Verify, T21, T18, T13, 45X, trisomy 21, trisomy 18, trisomy 13, turner syndrome, down syndrome, edward syndrome, patau syndrome, InformaSeq, Qnatal, Pregnancy Screen
2010232 Non-Invasive Prenatal Testing for Fetal Aneuploidy (Panorama) with Microdeletions Non-Invasive Prenatal Testing (Cell-Free DNA) NIPTANEUMD, Panorama, NIPD, Natera, Ariosa, Sequenom, Harmony, Verinata, Maternity 21, MaterniT21, Verifi, Verify, T21, T18, T13, 45X, trisomy 21, trisomy 18, trisomy 13, turner syndrome, down syndrome, edward syndrome, patau syndrome, Microdeletion, deletion, DiGeorge, Velocardiofacial, VCF, VCFS, 22q, del22, Angelman, Prader-Willi, 15q, PWS, 5p-, 5p, cri du chat, cri-du-chat, 1p36, InformaSeq, Qnatal, Pregnancy Screen
2013142 Non-Invasive Prenatal Testing for Fetal Aneuploidy with 22q11.2 Microdeletion (Panorama) Additional Technical Information Non-Invasive Prenatal Testing (Cell-Free DNA) NIPT ANEU, Panorama, NIPD, Natera, Ariosa, Sequenom, Harmony, Verinata, Maternity 21, MaterniT21, Verifi, Verify, T21, T18, T13, 45X, trisomy 21, trisomy 18, trisomy 13, turner syndrome, down syndrome, edward syndrome, patau syndrome, InformaSeq, Qnatal, Pregnancy Screen
0080269 Quad Screen Alpha Fetoprotein, hCG, Estriol, and Inhibin A Second-Trimester Screening AFP MS4, Prenatal Screening, nuchal translucency, NT, PN screen, Down, Downs, Down's, Trisomy 21, Trisomy 18, NTD, neural tube defects, two part screen, second trimester
0080434 Maternal Serum Screen, Alpha Fetoprotein (Only) Second-Trimester Screening MS ONLY, Prenatal Screening, NTD, neural tube defects, second trimester