Immunohistochemistry Stains

The ARUP Immunohistochemistry Laboratory performs more than 175 stains on formalin-fixed, paraffin-embedded tissues/cellblocks. These stains are used to detect the presence, abundance, and localization of specific proteins to aid in determining the direction of differentiation in neoplasms with similar morphology as well as to provide prognostic or therapeutic information, among other applications.

This lab is pathologist oriented, providing a stain and return service only, without interpretation, to our client pathologists to assist in their diagnostic studies. Most stains are returned the next day. The available stains are listed under the Stain and Return Immunohistochemistry tab. If interpretation is needed, please order a consultation.

For information concerning consultation, please call (801) 581-2507. Consultations can be sent directly to:

Surgical Pathology Department
Huntsman Cancer Hospital
1950 Circle of Hope, RM N3105
Salt Lake City, UT 84112
Phone: (801) 581-2507 or (801) 584-5078
Fax: (801) 581-7035

Please include pertinent clinical history and surgical pathology report.

The Immunohistochemistry Laboratory has a menu of immunohistochemistry tests for which we will provide interpretation by one of our ARUP faculty pathologists. A list of these tests can be found under the Immunohistochemistry Tests tab. The ARUP Immunohistochemistry Laboratory is an NSABP-approved laboratory for the testing of breast markers. Enhanced reports are available for Herceptin® and 4B5 testing.
Test # Test Name Test Keywords Additional Information
2007324 ALK (D5F3) with Interpretation by Immunohistochemistry ALKD5F3 IP Additional Technical Information
0049178 ERBB2 (HercepTest®) by Immunohistochemistry, Tissue with Reflex to FISH if 2+ Gastric, gastrointestinal cancer, tumor marker, pharmacogenetics, Breast Cancer, Tumor Markers, FISH, herceptin, HER2, HER-2, neu, HER2/neu, Pancreatic Cancer, Gastric Cancer, Barrett’s Esophagus Cancer, Gastroesophageal Junction Cancer
0049174 ERBB2 (HercepTest®) with Interpretation by Immunohistochemistry, Tissue Gastric, gastrointestinal cancer, tumor marker, pharmacogenetics, Breast Cancer, Tumor Markers, FISH, herceptin, HER2, HER-2, neu, HER2/neu, Pancreatic Cancer, Gastric Cancer, Barrett’s Esophagus Cancer, Gastroesophageal Junction Cancer
0049210 Estrogen/Progesterone Receptor with Interpretation by Immunohistochemistry Breast Cancer, Tumor Markers
2007357 IDH1 R132H Point Mutation with Interpretation by Immunohistochemistry IDH1 IP Additional Technical Information
2007182 Ki-67 with Interpretation by Immunohistochemistry
0049302 Mismatch Repair by Immunohistochemistry MSI, Hereditary Nonpolyposis Colorectal Cancer, HNPCC, Colorectal Cancer, Tumor Markers, MLH1, MSH2, MSH6, PMS2, mismatch repair, IHC, Lynch Additional Technical Information
2002327 Mismatch Repair by Immunohistochemistry with Reflex to BRAF Codon 600 Mutation and MLH1 Promoter Methylation Hereditary Nonpolyposis Colorectal Cancer, HNPCC, Colorectal Cancer, Tumor Markers, MSI, MLH1, MSH2, MSH6, PMS2, mismatch repair, IHC, Lynch
2005270 Mismatch Repair by Immunohistochemistry with Reflex to MLH1 Promoter Methylation MSI MLH1, Hereditary Nonpolyposis Colorectal Cancer, HNPCC, Colorectal Cancer, Tumor Markers, MLH1, MSH2, MSH6, PMS2, mismatch repair, IHC, Lynch Additional Technical Information
0049250 p53 with Interpretation by Immunohistochemistry Brain Tumors, Head and Neck Cancer, Chronic Lymphocytic Leukemia (CLL), Bladder Cancer, Ovarian Cancer, Hereditary Nonpolyposis Colorectal Cancer (HNPCC), Breast Cancer, Colorectal Cancer, Tumor Markers, Tumor suppressor protein, prognostic indicator, Non-small cell lung cancer, lung cancer
2012912 PD-1 by Immunohistochemistry with Interpretation Additional Technical Information
2013284 PD-L1 22C3 pharmaDx by Immunohistochemistry with Interpretation, pembrolizumab (KEYTRUDA)
2013684 PD-L1 28-8 pharmDx by Immunohistochemistry with Interpretation, nivolumab (OPDIVO)
2007031 PTEN with Interpretation by Immunohistochemistry
2008414 ROS1 with Interpretation by Immunohistochemistry with Reflex to FISH if Equivocal Additional Technical Information
2006948 SDHB with Interpretation by Immunohistochemistry