Cost Calculator: Chlamydia trachomatis screening

Chlamydia trachomatis

Chlamydia trachomatis is the most common STD in the United States (CDC, April 2009). In women, untreated infection may lead to pelvic inflammatory disease (PID), often requiring hospitalization; it can also lead to scarring of the fallopian tubes, a primary cause of female infertility.

These infections are treatable but often asymptomatic; many patients do not seek treatment. The U.S. Preventive Services Task Force and the CDC both recommend routine screening of sexually active women between the ages 15 and 25.

The most accurate diagnostic tests for C. trachomatis infection are nucleic acid amplification tests (NAAT). Non-amplified DNA probe tests are still commercially available, but are significantly less sensitive at detecting infection.

Chart Data

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Global Values

Prevalence:
Find your local prevalence
(%)
Patient Population:
 
Single Azithromycin
500mg:
($US)
Average Downstream Cost
of PID Complications:
($US)

Test Characteristics

Chlamydia trachomatis DNA Probe

Cost of Test:
($US)
Test Sensitivity:
(%)
Test Specificity:
(%)

Chlamydia trachomatis by Amplified Detection (APTIMA®)

Cost of Test:
($US)
Test Sensitivity:
(%)
Test Specificity:
(%)

Results

Chlamydia trachomatis DNA Probe

Test #0065059

Cost of Testing:
$15,000.00
Cost of Treating All Positives:
$2,377.50
Potential Cost of
False Negatives:
$759,000.00
Total Cost of Care:
$776,377.50

Chlamydia trachomatis by Amplified Detection (APTIMA®)

Test #0060243

Cost of Testing:
$30,000.00
Cost of Treating All Positives:
$1,012.50
Potential Cost of
False Negatives:
$165,000.00
Total Cost of Care:
$196,012.50
Difference in Testing Cost:
$15,000.00
Difference in Total Cost of Care:
$594,000.00

References

CDC information on screening for Chlamydia trachomatis

Hu D, Hook EW, Goldie SJ. Screening for Chlamydia trachomatis in women 15 to 29 years of age: a cost-effectiveness analysis. Ann Intern Med 2004;141(7):501–13. PMID: 15466767

Howell, M., et al. Screening women for Chlamydia trachomatis in family planning clinics: The cost-effectiveness of DNA amplification assays. Sex Transm Dis 1998;25(2):108–117. PMID: 9518379

Miller WC, et al. Prevalence of chlamydial and gonococcal infections among young adults in the United States. JAMA 2004;291(18):2229–36. PMID: 15138245

Honey, et al. Cost effectiveness of screening for Chlamydia trachomatis: a review of published studies. Sex Transm Infect 2002;78(6):406–12. PMID: 12473799

Trigg BG, Kerndt PR, Aynalem G. Sexually transmitted infections and pelvic inflammatory disease in women. Med Clin North Am 2008;92(5):1083–113; x. PMID: 18721654

Frenkl TL, Potts J. Sexually transmitted infections. Urol Clin North Am 2008;35(1):33–46; vi. PMID: 18061022

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