Current Posters and Presentations

Each year, the ARUP Institute for Clinical and Experimental Pathology® presents at more than 200 conferences, workshops, annual meetings, and symposiums for several national and international organizations. Recent posters and presentations are listed below.

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MARCH 2015

Endocrine Society (ENDO)
San Diego, CA, March 5–8, 2015

Kushnir MM, Rockwood AL, Strathmann FG, Straseski JA, Meikle AW—Poster
Kushnir MM, Rockwood AL, Strathmann FG, Straseski JA, Meikle AW. High-sensitivity measurement of parathyroid hormone-related protein in plasma using LC-MS/MS.

La'ulu SL, Straseski JA—Poster
La'ulu SL, Straseski JA. Zooming in on the low end: functional sensitivity of automated testosterone immunoassays.

United States and Canadian Academy of Pathology (USCAP)
Boston, MA, March 21–27, 2015

Bronner M, Rowe LR, Salama M—Poster
Jedrzkiewicz J, Bronner M, Downs-Kelly E, Rowe LR, Kohan J, Tai D, Salama M. Digital whole slide imaging and two photon microscopy for liver fibrosis scoring and quantification.

Andersen EF, Paxton CN, South S—Poster
O’Malley DP, Andersen EF, Paxton CN, Louissaint A, Hornick JL, Griffin GK, Fedoriw Y, Kim YS, Weiss LM, South S. Genetic array analysis of follicular dendritic cell sarcoma.

Salama ME, Hussong JW, Bahler DW—Poster
Van Ness M, Hill S, Salama ME, Hussong JW, Bahler DW. Limitations of flow cytometric analysis of CD200 expression In distinguishing chronic lymphocytic leukemia from mantle cell lymphoma.

Rowe LR, Kohan J, Prchal J, Salama ME—Poster
Rowe LR, Etman A, Kohan J, Prchal J, Ho G, Liu DQ, Salama ME. Stain-free detection and quantification of bone marrow fibrosis using two-photon excitation and second harmonic generation microscopy.

American College of Medical Genetics (ACMG)
Salt Lake City, UT, March 24–28, 2015

Wooderchak-Donahue W, Tvrdik T, Bayrak-Toydemir P—Poster
Wooderchak-Donahue W, Stevenson DA, McDonald J, Blei F, Berenstein A, Sorscher M, Tvrdik T, LaGrave D, Grimmer JF, Bayrak-Toydemir P. Expanding the clinical and molecular findings in cases with a RASA1 mutation.

Paxton CN, Perkins SL, South S—Poster
Paxton CN, Bellizzi AM, Alkapalan D, Fedoriw Y, O’Malley DP, Perkins SL, South ST, Andersen EF. Genomic analysis of juvenile xanthogranuloma.

South ST—Poster
Luem N, Hedlund G, Opitz J, Bleyl S, Sonnen J, South ST, Johnson D. Lissencephaly (syndrome) without lissencephaly?

Mass Spectrometry: Applications to the Clinical Laboratory (MSACL)
San Diego, CA, March 28–April 1, 2015

Rockwood AL, Kushnir MM—Poster
Bergquist M, Huss F, Fredén F, Hedenstierna G, Hästbacka J, Rockwood AL, Kushnir MM, Bergquist J. Altered adrenal and gonadal steroids biosynthesis in patients with burn injury.

Kushnir MM, Rockwood AL, Strathmann FG, Straseski JA, Meikle AW—Poster
Kushnir MM, Rockwood AL, Strathmann FG, Straseski JA, Meikle AW. High-sensitivity measurement of parathyroid hormone related protein by LC-MS/MS for diagnosing disorders of calcium regulation.

Khot P, Bird B, Fisher MA—Presentation
Khot P, Bird B, Durrant R, Fisher MA. Identification of Nocardia species by MALDI-TOF mass spectrometry.

Saraswat S, Bajaj A, Barker A—Poster
Saraswat S, Bajaj A, Barker A. Identifying the proteome of different mycobacterial species using Orbitrap mass spectrometry.

Marin SJ, McMillin GA, Strathmann FG—Poster
Marin SJ, McMillin GA, Strathmann FG. Is it noroxymorphone or nornaloxone, and why should you care?

Merrigan SD, Johnson-Davis K—Poster
Merrigan SD, Johnson-Davis K. LC-MS/MS method for quantitative analysis of gabapentin and pregabalin in serum or plasma.

Kushnir MM, Rockwood AL—Poster
He L, Kushnir MM, Rockwood AL. Optimization of LC-MS/MS method for thyroglobulin quantitation in human serum.

Ray JA, Rasmussen N, La’ulu S, Rockwood AL, Strathmann FG—Presentation
Ray JA, Sadjadi S, Rasmussen N, La’ulu S, Rockwood AL, Strathmann FG. Recurrent need for a robust method for measuring T3/rT3 by LC-MS/MS: An exercise in madness or a new beginning for a misused marker?

Rule GS, Rockwood AL—Poster
Rule GS, Doyle K, Rockwood AL. Use of 96-well pipetting workstation for liquid-liquid extraction of adrenal steroids.

Rule G, Rockwood AL—Poster
Rule G, Doyle K, Rockwood AL. Validation of a 96-well method for liquid-liquid extraction of pregnenolone and 17-hydroxypregnenolone from human serum and plasma.

Society for Inherited Metabolic Disorders (SIMD)
Salt Lake City, UT, March 28–31, 2015

De Biase I, Liu A, Yuzyuk T, Pasquali M—Poster
De Biase I, Liu A, Yuzyuk T, Pasquali M. Argininosuccinic acid detection by liquid chromatography tandem mass spectrometry: clinical implications.

FEBRUARY 2015

EUROGIN 2015
Sevilla, Spain, February 4–7, 2015

Tardif K, Pyne M, Malmberg E, Lunt T, Schlaberg R—Poster
Tardif K, Pyne M, Malmberg E, Lunt T, Schlaberg R. Cervical cytology specimen stability in Surepath preservative and analytical sensitivity for HPV testing with the COBAS® (Roche) and Hybrid Capture 2® (Qiagen) test.

DECEMBER 2014

American Society for Hematology (ASH)
San Francisco, CA, December 6–9, 2014

Szankasi P, Schumacher JA, Kelley TW—Poster
Szankasi P, Schumacher JA, Efimova O, Kelley TW. A recurrent T-cell receptor y rearrangement of the Vy9-JyP rype represents the major clone of yo T-cells in normal individuals and is highly suppressed in lymphoproliferative disorders.

Perkins SL, Bahler DW—Poster
Klinger M, Faham M, Zheng J, Elenitoba-Johnson K, Perkins SL, Bahler DW. Next-generation IgVH sequencing of monoclonal B-cell lymphocytosis reveals clonal heterogeneity, ongoing somatic hypermutation, and repertoire differences relative to chronic myelomonocytic leukemia.

Kelley TW—Poster
Mason CC, Khorashad JS, Tantravahi SK, Kelley TW, Pomicter AD, Iovino AJ, Reynolds KR, Eiring AM, Zabriskie MS, Kronenberg Z, Tyner JW, Dalley B, Dao KH, O'Hare T, Yandell M, Druker BJ, Gotlib JR, Deininger MW. Next- generation sequencing to delineate the mutational landscape of chronic myelomonocytic leukemia (CMML): novel disease genes and correlations with survival.

NOVEMBER 2014

American Association of Pharmaceutical Sciences (AAPS)
San Diego, CA, November 2–6, 2014

Johnson-Davis KL, McMillin GA—Poster
Campbell SC, Johnson-Davis KL, Linakis MW, McMillin GA, Sherwin CMT, Spigarelli MG. Evaluating the relationship of age and thiopurine metabolites in pediatrics.

Association for Molecular Pathology (AMP)
Washington, DC, November 12–15, 2014

Szankasi P, Durtschi J, Schumacher JA, Kelley TW—Poster
Szankasi P, Durtschi J, Fisher DM, Schumacher JA, Kelley TW. A 51-gene NGS panel for diagnosis and risk assessment in myeloid malignancies.

Lyon E—Presentation
Lyon E, McDonough R, Aronson N. Evidence basis and clinical utility for molecular testing.

Hanson KE—Presentation
Hanson KE. Fungal molecular diagnostics: recent advances and ongoing challenges.

Schumacher JA, Szankasi P, Kelley TW—Poster
Schumacher JA, Efimova O, Szankasi P, Kelley TW. Optimization of PCR primers for unbiased amplification of the TRG repertoire for next generation sequencing.

Millson A, Lewis T, Lyon E, Bayrak-Toydemir P—Poster
Millson A, Lewis T, Pesaran T, Salvador D, Gillespie K, Gau CL, Lyon E, Bayrak-Toydemir P. Processed pseudogene confounding deletion/duplication assays for SMAD4.

Reading NS, Schumacher JA, Kelley TW—Poster
Reading NS, Schumacher JA, Kelley TW. A novel method for inv(16);CBFB-MYH11 fusion gene quantitation by real-time PCR using single-concentration calibrator plasmids.

Bastien RRL, Welker NC, Margraf RL, Durtschi J, Elsberry D, Bernard PS, Samowitz WS, Vaughn CP—Poster
Bastien RRL, Welker NC, Margraf RL, Durtschi J, Elsberry D, Bernard PS, Samowitz WS, Vaughn CP. Simultaneous detection of fusion transcripts and small alterations in lung adenocarcinoma by next-generation sequencing.

Jama MA, Lyon E—Poster
Jama MA, Lyon E. Allele sizing from Abbott/Celera’s FRM1 triplet repeat primed PCR assay.

Geiersbach K, Welker N, Elsberry D, Salama M, Bronner M—Poster
Geiersbach K, Adey N, Welker N, Elsberry D, Downs-Kelly E, Salama M, Bronner M. Milling microdissection ensures reliable tumor content for molecular testing without sacrificing yield.

Reading NS, Schumacher JA, Kelly TW—Poster
Reading NS, Schumacher JA, Kelly TW. A novel method for inv(16);CBFß-MYH11 fusion gene quantitation by real-time PCR using single-concentration calibrator plasmids.

Baker CL, Baker D, Vaughn CP, Samowitz WS—Poster
Baker CL, Nix D, Baker D, Fisher D, Vaughn CP, Samowitz WS, Grossmann A. A novel approach to translocation detection with next-generation sequencing using formalin-ixed, paraffin-embedded sarcomas.

Liew M, Mao R, Wittwer CT, Salama M—Poster
Liew M, Mao R, Wittwer C, Salama M. Performance of the n-counter system for detection of chromosomal translocations in formalin-fixed, parrafin embedded (FFPE) leukemic specimens.

Margraf RL, Dames S, Durtschi J, Mao R, Voelkerding K—Poster
Margraf RL, Dames S, Durtschi J, Mao R, Voelkerding K. Evaluation of the Illumina NextSeq500 for rapid whole genome sequencing.

American College of Rheumatology (ACR)/Association of Rheumatology Health Professionals (ARHP)
Boston, MA, November 14–19, 2014.

Heikal N, Jaskowski TD, Malmberg E, Tebo AE—Poster
Heikal N, Jaskowski TD, Malmberg E, Lakos G, Branch DW, Tebo AE. Antiphospholipid antibodies in a prospective patient population at-risk for antiphospholipid syndrome or with associated clinical manifestations.

OCTOBER 2014

Swedish Society of Mass Spectrometry (SSMS)
Stockholm, Sweden, October 5–7, 2014

Kushnir MM, Rockwood AL, Strathmann FG, Meikle AW—Presentation
Kushnir MM, Rockwood AL, Strathmann FG, Meikle AW. High-sensitivity measurement of thyroglobulin by LC-MS/MS for monitoring recurrence of thyroid cancer.

Eurolab Focus
Liverpool, England, October 7–10, 2014

Kushnir MM—Poster
Büttler RM, Martens F, Kushnir MM, Ackermans MT, Blankenstein MA, Heijboer AC. Measurement of serum testosterone, androstenedione, and DHEA levels using isotope-dilution liquid-chromatography tandem mass spectrometry.

American Society for Clinical Pathology (ASCP)
Tampa, FL, October 8–10, 2014

Heikal N, Pavlov I, Salama ME, Delgado J—Poster
Heikal N, Pavlov I, Salama ME, Delgado J, Camp NJ, Halwani A. Soluble CD30 levels in chronic lymphocytic leukemia/ small lymphocytic lymphoma patients.

Infectious Disease Society of America (IDSA)
Philadelphia, PA, October 8–12, 2014

Couturier BA, Kalp K—Poster
Couturier BA, Kalp K, Ginocchio C, Schlaberg R. Detection and differentiation of Babesia microti and other pathogenic Babesia species by a single-amplicon, dual-probe, real-time PCR assay.

Couturier M—Presentation
Couturier M. Molecular diagnosis of gastroenteritis/acute diarrhea.

Schlaberg R, Tardif K, Hymas W—Poster
Schlaberg R, Ampofo K, Tardif K, Stockmann C, Simmon K, Hymas W, Flygare S, Kennedy B, Blashke A, Eileck K, Yandall M, Bramley A, Jain S, Pavia A. Can human bocavirus mRNA detection differentiate acute infection from viral shedding?

Couturier B, Malmberg E, Kalp K, Lunt T, Schlaberg R—Poster
Couturier B, Malmberg E, Kalp K, Lunt T, Schlaberg R. Trichomonas vaginalis prevalence in the United States.

Schlaberg R, Tardif K, Voelkerding K—Poster
Schlaberg R, Queen K, Simmon K, Tardif K, Stockmann C, Flygare S, Kennedy B, Voelkerding K, Bramley A, Eilbeck K, Yandell M, Jain S, Pavia A, Tong S, Ampofo K. Viral pathogen detection by metagenomics and panviral PCR in children with pneumonia with no identifiable etiology: preliminary results from the CDC etiology of pneumonia in the community (EPIC) study.

AACC: Mass Spectrometry in the Clinical Lab: Best Practices and Current Applications
St. Louis, MO, October 9, 2014

Strathmann F—Presentation
Strathmann F. The laboratory’s role in pain management testing.

American College of Clinical Pharmacy (ACCP)
Austin, TX, October 12–15, 2014

Johnson-Davis KL, McMillin GA—Poster
Linakis MW, Campbell SC, Stockmann C, Johnson-Davis KL, McMillin GA, Sherwin CMT, Spigarelli MG. Regional differences in thiopurine methyltransferase activity.

American Society of Histocompatibility and Immunogenetics (ASHI)
Denver, CO, October 20–24, 2014

Profaizer T, Coonrod E, Delgado J, Kumanovics A—Poster
Profaizer T, Coonrod E, Delgado J, Kumanovics A. Evaluation of enzymatic library preparation for the Illumina MiSeq.

Heikal N, Pavlov I, Salama ME, Delgado J—Poster
Heikal N, Pavlov I, Salama ME, Delgado J, Camp NJ, Halwani A. Soluble CD30 levels in chronic lymphocytic leukemia / small lymphocytic lymphoma patients.

American Society of Human Genetics (ASHG)
San Diego, CA, October 18–22, 2014

Sumner K, Damjanovich K, Bayrak-Toydemir P, Best DH—Poster
Sumner K, Damjanovich K, Smith B, Nakayama I, Ha Y, Paul E, Morris A, Brown LM, Bayrak-Toydemir P, Elliott CG, Best DH. Prevalence of EIF2AK4 gene mutations in patients with a clinical diagnosis of pulmonary arterial hypertension.

Society of Forensic Toxicologists (SOFT)
Grand Rapids, MI, October 19–24, 2014

Marin SJ, McMillin GA—Poster
Marin SJ, Metcalf A, McMillin GA. Comparison of methods for extraction of drugs from umbilical cord tissue.

Slawson MH, Johnson-Davis KL—Poster
Slawson MH, Kero F, Vandell V, Cherrier M, Williams L, Johnson-Davis KL. LC-MS/MS analysis of ethyl glucuronide and ethyl sulfate: a comparison of sample preparation techniques.

Marin SJ, Johnson-Davis KL—Poster
Marin SJ, Chang A, Doyle K, Johnson-Davis KL. LC-TOF-MS analysis of 100 false positive amphetamine immunoassay urine specimens.

Marin SJ, Strathmann FG—Presentation
Hill B, Clark CJ, Marin SJ, Strathmann FG. Optimized umbilical cord homogenization for the detection of in utero drug exposure by liquid chromatography time-of-flight mass spectrometry.

Haglock-Alder CJ, Strathmann FG—Poster
Haglock-Adler CJ, Strathmann FG. Reduced sample volume and simplified sample preparation in the simultaneous measurement of zinc, antimony, bismuth, and manganese in whole blood using inductively coupled plasma-mass spectrometry.

SEPTEMBER 2014

PAINWeek
Las Vegas, NV, September 8–12, 2014

McMillin GA, Marin SJ, Johnson-Davis KL, Strathmann FG—Poster
McMillin GA, Marin SJ, Johnson-Davis KL, Lawlor BG, Strathmann FG. An alternative strategy for pain management compliance testing using a combination of immunoassay and time-of-flight mass pectrometry.

Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC)
Washington, DC, September 5–9, 2014

Fisher MA—Poster
Boyd NK, Lee GC, Reveles KR, Frei CR, Fisher MA. Large-scale analysis of antimicrobial activities against bacteroides collected nationwide from 2003 to 2013.

AUGUST 2014

Association of Medical and Laboratory Immunologists (AMLI)
Seattle, WA, August 9–12, 2014

Heikal N, Jaskowski TD, Malmberg E, Tebo AE—Poster
Heikal N, Jaskowski TD, Malmberg E, Lakos G, Branch DW, Tebo AE. Antiphospholipid antibodies in a prospective patient population at risk for atiphospholipid syndrome or with associated clinical manifestations

Pavlov IY—Presentation
Pavlov IY. Assay for neutralizing antibody against anti-TNF drugs: in-silica experiments.

Jaskowski TD, Malmberg E, Tebo AE—Poster
Nandiwada S, Mayes MD, Jaskowski TD, Malmberg E, Satoh M, Tebo AE. Autoantibody specificities of anti-nucleur antibodies in systemic sclerosis is hghly dependent on racial background.

Ravkov E, Slev P, Heikal N—Poster
Ravkov E, Slev P, Heikal N. Correlation between recent thymic emigrants and T-cell receptor excision circles in newborn screening for SCID.

Jaskowski TD, Tebo AE—Poster
Jaskowski TD, Tebo AE. Detection of autoantibodies in myositis and associated connective tissue diseases: an extended approach by immunoprecipitation assay

Haven TR, Tebo AE—Poster
Haven TR, Knapp D, Tebo AE. Detection of autoantibodies to leucine-rich glioma inactivated 1 and contactin-associated protein-like 2 receptors by recombinant cell immunofluorescence.

Kumanovics A, Hill HR—Poster
Lazar-Molnar E, Kumanovics A, Hill HR. Development of a non-radioactive lymphocyte proliferation assay for the clinical laboratory.

Cancer Genomics Consortium and Cytogenomics Array Group (CGC-CAGdb)
Chicago, IL, August 11–13, 2014

South ST—Presentation
Hirsch B, Smolarek T, South ST. Challenging and teaching cases.

National Society for Histotechnology (NSH)
Austin, TX, August 22–27, 2014

Tripp S, Salama ME—Poster
Tripp S, Salama ME. Programmed cell death 1 ligand 1 (PD-L1) expression in diffuse large B-cell lymphoma.

JULY 2014

American Association for Clinical Chemistry (AACC)
Chicago, IL, July 27–31, 2014

Grenache DG—Poster
Sowder A, Yarbrough ML, Nerenz R, Mortensen R, Gronowski AM, Grenache DG. An analytical evaluation of the Abbott i-STAT hCG test cartridge.

Perkins S—Presentation
Perkins S. Anemias.

Straseski JA—Presentation
Straseski JA. Banking on the numbers: laboratory assessment of ovarian reserve.

Clark ZD, Frank EF—Poster
Clark ZD, Frank EF. C-ing is believing: enhanced specificity for vitamin C using HPLC with electrochemical detection and automatic alternating column regeneration.

Lyon E— Presentation
Lyon E. Comparing sequencing to high resolution melting in CFTR whole gene analysis.

Slev P—Presentation
Slev P. Developments in HIV testing.

Schmidt RL, La'ulu SL, Hanson SE—Poster
Schmidt RL, La'ulu SL, Hanson SE, Rohlfing CL, Little RR. Effects of 49 different rare variants on HbA1c measurements in seven methods.

Grenache DG—Presentation
Grenache DG. Four reasons for a positive hCG test in the absence of pregnancy.

Genzen JR—Presentation
Genzen JR. Fundamentals of critical values: policies, problems and proposed solutions.

Grenache DG—Poster
Suh-Lailam B, Grenache DG. Identifying G6PD deficiency: defining the lower reference limit and evaluating pre-analytical sources of error.

Straseski JA—Presentation
Straseski JA. Interpretation of insulin and C-peptide immunoassay results: using cross reactivity and interferences to your advantage.

Wittwer CT—Presentation
Wittwer CT. Introduction to sequencing and high resolution melting.

Lyon E—Presentation
Lyon E. Molecular pathology coding.

Lu J, Grenache DG—Poster
Lu J, Grenache DG. Performance evaluation of the AnshLite myelin basic protein chemiluminescent immunoassay using cerebrospinal fluid.

Erickson JA, Grenache DG—Poster
Erickson JA, Jensen RA, Grenache DG. Performance evaluation of a polyclonal based fecal alpha-1-antitrypsin ELISA.

La'ulu SL, Strathmann FG, Genzen JG—Poster
Scholes KL, La'ulu SL, Ence AT, Logan HL, Parker RL, Strathmann FG, Genzen JG. Performance evaluation of rapid test strips for the identification of EDTA-containing specimens.

Rockwood AL— Presentation
Rockwood AL. Preventative maintenance - the key to sleeping well after implementing.

Liu A, Erali M, Longo N, Pasquali M, De Biase I—Poster
Liu A, Hobert J, Erali M, Pickering J, Longo N, Pasquali M, De Biase I. Quantitative amino acid analysis using liquid chromatography tandem mass spectrometry and aTRAQ reagents. Do we have a new gold standard?

Grenache DG—Poster
Hackenmueller SA, Grenache DG. Reference intervals for intestinal dissacharidase activity determined from a non-reference population.

Kushnir MM, Rockwood AL, Meikle AW—Poster
Kushnir MM, Rockwood AL, Meikle AW. Serum thyroglobulin measurement in autoantibody positive samples by LC-MS/MS and immunoassay: is positivity rate different between the methods?

Grenache DG—Presentation
Grenache DG. The many faces of hCG.

La'ulu SL, Straseski JA, Genzen JR—Poster
La'ulu SL, Straseski JA, Genzen JR. Thrombin mediated degradation of parathyroid hormone in serum tubes.

Johnson-Davis KL—Presentation
Johnson-Davis KL. Urine drug testing for opiate use and abuse.

JUNE 2014

Canadian Society of Clinical Chemists
Charlottetown, Canada, June 8–11, 2014

McMillin GA—Presentation
McMillin GA. Genetics of therapeutic drug response.

American Society for Mass Spectrometry (ASMS)
Baltimore, MD, June 15–19, 2014

Escobar H, Rockwood AL, Kushnir MM, Meikle AW—Poster
Escobar H, Rockwood AL, Kushnir MM, Meikle AW. Direct measurement of pancreatic polypeptide in human serum and plasma by immunocapture-liquid-chromatography-tandem mass spectrometry.

European Symposium of Biopathology
Paris, France, June 19–21, 2014

South ST—Presentation
South ST. Detection of copy number alterations, ploidy, and loss of heterozygosity across the genome in FFPE specimens: utility for diagnosis and treatment with comparison between FISH-based and as a complement to sequencing assays.

Serbian Diaspora Medical Conference
White Palace, Belgrade, June 19–21, 2014

South ST—Presentation
South ST. Implementing arrays for cytogenetic applications: A discussion of best practices for platform validation, analysis, and interpretation.

Endocrine Society (ENDO)
Chicago, IL, June 21–24, 2014

Lu J, Kalp K, Straseski J—Poster
Lu J, Holt C, Choi M, Kalp K, Straseski J. Analytical evaluation of the AnshLabs anti-müllerian hormone picoAMH ELISA assay.

Kushnir MM, Rockwood AL, Meikle AW—Poster
Kushnir MM, Rockwood AL, Meikle AW. Observational study of data on analysis of thyroglobulin in autoantibody positive samples using commercial immunoassay and LC-MS/MS methods.

Wyness SP, Straseski JA—Poster
Wyness SP, Straseski JA. Performance characteristics of six automated 25-hydroxy vitamin D assays: mind your 3’s and 2’s.