Current Posters and Presentations
Each year, the ARUP Institute for Clinical and Experimental Pathology® presents at more than 200 conferences, workshops, annual meetings, and symposiums for several national and international organizations. Recent posters and presentations include:
International Society for the Study of Vascular Anomalies (ISSVA)
Melbourne, Australia, April 2–4, 2014
Wooderchak-Donahue WL, Durtschi J, Sumner K, Lewis T, Best H, Bayrak-Toydemir P—Presentation
Wooderchak-Donahue WL, McDonald J, Durtschi J, Sumner K, Lewis T, Stocks J, Stevenson DA, Grimmer JF, Best H, Bayrak-Toydemir P. Clinical utility of a next-generation sequencing panel in the diagnosis of hereditary hemorrhagic telangiectasia (HHT) and other syndromes featuring vascular.
Wooderchak-Donahue WL, Bayrak-Toydemir P—Poster
Wooderchak-Donahue WL, Blei F, Berenstein A, McDonald J, Sorscher M, Bayrak-Toydemir P. Novel RASA1 splice site mutation identified in an infant prenatally diagnosed with cerebral arteriovenous fistula-type (AVF) malformation.
American Association for Cancer Research (AACR)
San Diego, CA, Apr 5–9, 2014
Magdaleno SM, Cheng A, Petraroli R, Sheils O, Tops B, Le Corre D, Kurth H, Blons H, Amato E, Mafficini A, Rachiglio AM, Reimann A, Noppen C, Ainali C, Katayama J, Franco R, Feilotter H, Schageman J, Cree I, Felton A, Costa JL, Rico A, Scarpa A, Machado JC, Nishio K, Normanno N, Ligtenberg M, Vaughn CP, Lacroix L, Laurent-Puig P. The OncoNetwork Consortium: a global collaborative research study on the development and verification of an Ion AmpliSeq RNA gene lung fusion panel.
Thrombosis and Hemostasis Summit of North America (THSNA)
Chicago, IL, April 10–12, 2014
Hsu P, Marlar RA, Zantek ND, Smock KJ, Plumhoff E, Meijer P, Van Cott EM. Activated protein C resistance testing: assessment of the quality of testing performed by North American specialized coagulation laboratories.
Smock KJ. Is there a role for laboratory testing for aspirin and clopidogrel effect?
Smock KJ, Heikal NM—Poster
Smock KJ, Plumhoff EA, Meijer P, Hsu P, Zantek ND, Heikal NM, Van Cott EM. Protein S: quality of testing in North American specialized coagulation laboratories.
Zantek ND, Hsu P, Meijer P, Plumhoff EA, Refaai MA, Smock KJ, Van Cott EM. Quality of factor XI testing in North American specialized coagulation laboratories.
Smock KJ. Protein S testing update.
Clinical Immunology Society (CIS)
Baltimore, MD, April 10–13, 2014
Coonrod EM, Durtschi J, Hill HR, Voelkerding KV, Kumanovics A—Poster
Coonrod EM, Durtschi J, Hill HR, Voelkerding KV, Kumanovics A. Performance of next-generation-sequencing-based gene panels for primary immunodeficiencies.
Pan American Society for Clinical Virology (PASCV)
Daytona, FL , April 25–30, 2014
Pyne MT, Hillyard DR—Poster
Pyne MT, Hillyard DR. Evaluation of the Roche CAP/CTM HCV Test, v2.0.
Tardif KD, Schlaberg R—Poster
Tardif KD, Prichard M, Schlaberg R. Simultaneous titration and antiviral drug susceptibility testing for HSV1 and 2.
Mass Spectrometry Applications to the Clinical Lab (MSACL)
San Diego, CA, March 1–5, 2014
Ray JA, Kushnir MM, Rockwood AL, Meikle AW—Presentation
Ray JA, Kushnir MM, Rockwood AL, Meikle AW. Aldosterone by LC-MS/MS: cost saving not at the cost of patient care.
Suh-Lailam BB, Rule GS, Johnson-Davis KL—Poster
Suh-Lailam BB, Rule GS, Johnson-Davis KL. Development and validation of a liquid chromatography-tandem mass spectrometry assay for the detection of nine oral antidiabetic drugs in plasma and urine.
Marin SJ, Johnson-Davis KL—Poster
Marin SJ, Sawyer J, Johnson-Davis KL. Evaluation of three quadrupole time of flight mass spectrometry (QTOF) platforms for targeted screening of drugs and metabolites.
Slawson MH, Johnson-Davis, KL—Poster
Slawson MH, Johnson-Davis, KL. LC-MS/MS analysis of ethyl glucuronide in urine: a case study in ion suppression.
Merrigan SD, Kish-Trier E, Johnson-Davis K—Poster
Merrigan SD, Kish-Trier E, Seegmiller J, Johnson-Davis K. LC-MS/MS method for quantitative analysis of mycophenolic acid and two of its major metabolites, mycophenolic Acid glucuronide and mycophenolic acid acyl-glucuronide, in serum.
Kish-Trier E, Merrigan S, Johnson-Davis KL—Poster
Kish-Trier E, Merrigan S, Seegmiller J, Johnson-Davis KL. LC-MS/MS method for quantitative analysis of thiopurine drug metabolites in whole blood.
Kushnir MM, Rockwood AL, Straseski JA, Meikle AW—Poster
Kushnir MM, Rockwood AL, Ohman T, Carlisle HJ, Straseski JA, Meikle AW. Measurement of thyroglobulin in fine-needle aspiration samples: comparing LC-MS/MS to an immunoassay.
Haglock-Adler CJ, Strathmann FG—Presentation
Haglock-Adler CJ, Strathmann FG. Reduced sample volume and simplified sample preparation in the simultaneous measurement of zinc, antimony, bismuth, and manganese in whole blood using ICP-MS.
Rule G, Rockwood AL—Poster
Rule G, Carlisle H, Ohman T, Holt B, Rockwood AL. Reducing the need for calibration standards.
Clark Z, McMillin GA, Strathmann FG—Poster
Clark Z, McMillin GA, Strathmann FG. Three strategies to stop a pervasive high-throughput sample preparation quality problem you likely didn’t know you had.
Hackenmueller SA, Strathmann FG—Presentation
Hackenmueller SA, Strathmann FG. Use of isocratic pump direct injection and inductively coupled plasma-mass spectrometry for analysis of lead in 20 uL of whole blood.
United States and Canadian Academy of Pathology (USCAP)
San Diego, CA, March 1–7, 2014
Pham HT, Nussenzveig RH, Lyon E, Salama ME, Wittwer C, Agarwal AM–Poster
Pham HT, Nussenzveig RH, Lyon E, Salama ME, Wittwer C, Agarwal AM. Temperature Calibration of Well-to-Well Variation during High-Resolution Melt Analysis by Novel Unlabeled Stem-Loop Oligonucleotides.
Nussenzveig RH, Pham HT, Perkins SL, Prchal JT, Agarwal AM, Salama ME–Presentation
Nussenzveig RH, Pham HT, Perkins SL, Prchal JT, Agarwal AM, Salama ME. High Frequency of Coexisting JAK2 Exon-12 or MPL Exon-10 Mutations in Patients with Low JAK2V617F Allelic Burden: A New Clinical Paradigm?
Schumacher JA, Kelley TW, Duncavage E—Poster
Sufficool K, Lockwood C, Hagemann I, Schumacher JA, Kelley TW, Duncavage E. Detection of T-cell clonality by next-generation sequencing in mycosis fungoides.
Vaughn CP, Samowitz WS—Poster
Weidner AS, Panarelli NC, Yantiss RK, Vaughn CP, Samowitz WS, Chen YT. Immunohistochemical and molecular evaluation of BRAF mutations in tumors of the serrated neoplastic pathway.
Schumacher JA, Kelley TW—Poster
Sufficool KE, Lockwood CM, Hagemann IS, Schumacher JA, Kelley TW, Duncavage EJ. Detection of T-cell clonality by next-generation sequencing in mycosis fungoides.
Pham HT, Nussenzveig RH, Lyon E, Salama ME, Wittwer C, Agarwal AM—Poster
Pham HT, Nussenzveig RH, Lyon E, Salama ME, Wittwer C, Agarwal AM. Temperature calibration of well-to-well variation during high-resolution melt analysis by novel unlabeled stem-loop oligonucleotides.
Nussenzveig RH, Pham HT, Perkins SL, Prchal JT, Agarwal AM, Salama ME—Presentation
Nussenzveig RH, Pham HT, Perkins SL, Prchal JT, Agarwal AM, Salama ME. High frequency of coexisting JAK2 exon-12 or MPL exon-10 mutations in patients with low JAK2V617F allelic burden: a new clinical paradigm?
Dubai International Pharmaceuticals and Technologies Conference (DUPHAT)
Dubai, March 10–12, 2014
McMillin GA. Detection of in utero (prenatal) drug exposures.
McMillin GA. An overview of clinical pharmacogenetics implementation in the U.S.
American College of Medical Genetics (ACMG)
Nashville, TN, March 25–29, 2014
Martin M, Bisson R, Vanzo R, Sdano M, South ST, Deak K. Aggarwal VA familial FLCN whole gene deletion identified on CMA: the challenge of incidental findings.
Sdano M, Martin M, Vanzo R, Deak K, Aggarwal V, South ST.
Another look at sibling testing strategies: should patients with non-specific neurodevelopmental features be treated differently?
South ST. Concordance and utility of genomic microarray fata for leukemia: results from a pilot COG study.
Procter M, Mao R—Poster
Procter M, Mao R. Nineteen novel mutations causing biotinidase deficiency.
Sederberg M, South ST, Toydemir R—Poster
Sederberg M, South ST, Toydemir R, Rope A. Pallister-Killian syndrome in a girl due to mosaic hexasomy 12p.
Wooderchak-Donahue W, Lewis T, Tvrdik T, Bayrak-Toydemir P—Poster
Wooderchak-Donahue W, VanSant-Webb C, Tvrdik T, Lewis T, Plant P, Stocks J, Raney J, Wayman T, O’Fallon B, Rope AF, Yetman AT, Bull D, Bayrak-Toydemir P. Clinical utility of a next-generation sequencing panel assay for Marfan and Marfan-like syndromes featuring aortopathy.
American Federation for Medical Research (AMFR) Western Regional Meeting
Carmel, CA, January 23–25, 2014
Martins TB, Tardif KD, Augustine NH, Kumanovics A, Hill HR—Poster
Martins TB, Woodbury KO, Tardif KD, Augustine NH, La Pine TR, Kumanovics A, Hill HR. Increased pro-inflammatory cytokine expression in response to TLR3 and TLR9 stimulation using HSV1.
Association for Molecular Pathology (AMP)
Phoenix, AZ, November 14–16, 2013
Mitchell SM. RNA extraction from whole blood and bone marrow using simply RNA on the Maxwell 16 instrument.
Schumacher JA, Szankasi P, Kelley TW—Poster
Schumacher JA, Szankasi P, Kelley TW. A comparison of PCR primer sets for enrichment of TCRG rearrangements for next-generation sequencing of the T-cell gamma repertoire.
Wallander ML, Redpath S, Banks PM, Layfield LJ. Comparison of dual-ISH (DISH) and fluorescence in-situ hybridization (FISH) methodologies for the determination of HER2 status in breast carcinoma.
Szankasi P, Kelley TW—Poster
Szankasi P, Anderson D, Kelley TW. Comparison of quantitative BCR-ABL1 PCR testing results on paired peripheral blood/bone marrow aspirate specimens.
Coonrod EM, Durtschi J, Hill HR, Voelkerding KV, Kumanovics A—Poster
Coonrod EM, Durtschi J, Hill HR, Voelkerding KV, Kumanovics A. Performance of haloplex custom capture for clinical testing of primary immunodeficiencies by next-generation sequencing.
Schlaberg R. Sequencing for microorganism identification and characterization.
Sumner K, Swensen JJ, Lewis T, Wooderchak-Donahur W, Fong M, Brulotte B, Bayrak-Toydemir P, Pont-Kingdon G, Best DH—Poster
Sumner K, Swensen JJ, Lewis T, Wooderchak-Donahur W, Fong M, Brulotte B, Bayrak-Toydemir P, Pont-Kingdon G, Best DH. The clinical advantage of noncontiguous loop-out primers in the avoidance of problematic DNA sequences.
Elsberry D, Welker NC, Bronner MP—Poster
Elsberry D, Welker NC, Cho M-Y, Kim I-Y, Wilson AR, Bronner MP. Utility of thymidylate synthase genotyping for 5-fluorouracil chemotherapy in a large, colorectal cancer cohort study.
American Society for Histocompatibility and Immunogenetics (ASHI)
Chicago, IL, November 17–18, 2013
Profaizer T, Coonrod E, Delgado J, Kumanovics AA—Poster
Profaizer T, Coonrod E, Delgado J, Kumanovics AA. A comparison of physical and enzymatic fragmentation methods in library preparation for HLA sequencing on the Illumina MISEQ.
National Society of Genetic Counselors (NSGC)
Anaheim, CA, October 9–12, 2013
Calhoun MR, Carey JC, Hammond P, Lortz A, South ST, Rope A. Morphogenesis of the face in Wolf-Hirschhorn: three informative cases.
American College of Gastroenterology (ACG)
San Diego, CA, October 11–16, 2013
Delgado JC, Pavlov IY—Poster
Delgado JC, Pavlov IY, Kusukawa N, Skodack LA. Clinical laboratory validation of a functional assay for monitoring infliximab biological activity and neutralizing anti-infliximab antibodies.
North American Cystic Fibrosis Conference (NACFC)
Salt Lake City, UT, October 17–19, 2013
Lyon E , Groo B, Zhou L, Pham H, Nelson B, Wittwer C—Poster
Lyon E , Groo B, Zhou L, Pham H, Nelson B, Wittwer C. Full CFTR gene analysis using high-resolution melting as a second-tier test for newborn screening: a comprehensive approach.
American Society of Human Genetics (ASHG)
Boston, MA, October 22–26, 2013
Margraf RL, Coonrod EM, Durtschi J, Kumanovics A, Voelkerding KV—Poster
Margraf RL, Coonrod EM, Durtschi JD, Mallempati K, Kumanovics A, Newcomb TM, Optiz JM, Carey JC, Zhou H, Katz BE, Voelkerding KV, Swoboda KJ. A novel germline PIGA mutation in Ferro-Cerebro-Cutaneous syndrome: a neurodegenerative X-linked encephalopathy with epilepsy and systemic iron-overload.
Millson A, Lyon E—Poster
Millson A, Miller C, Lyon E. Classification and interpretation of CFTR, PRSS1, and SPINK1 sequence variants found in idiopathic and hereditary pancreatitis.
Sant DW, Margraf RL, Durtschi J, Voelkerding KV—Poster
Sant DW, Margraf RL, Durtschi J, Voelkerding KV. De novo germline mutations in MYL3 and DYNC1H1 genes discovered by exome sequencing in an infant with congenital joint contractures.
Fisch GS, South ST, Rutherford A, Falk R, Carey J. Deletion 2q37: cognitive-behavioral profiles, developmental trajectories, and IQ related to deletion size.
American College of Rheumatology (ACR)/Association of Rheumatology Health Professionals (ARHP)
San Diego CA, October 25–30, 2013
Tebo A, Willis R, Jaskowski T, Madger L, Petri M, Pierangeli S, Branch DW. Association of anti-B2glycoprotein i antibodies in a large cohort of lupus patients.
Tebo AE, Jaskowski TD—Poster
Tebo AE, Willis R, Jaskowski TD, Salmon JE, Petri M, Branch WD, Pierangeli SS. Isotype-dependent performance of b2glycoprotein I immunoassays in two diverse patient cohorts: implications for assay harmonization and standardization.
American College of Rheumatology (ACR)/
Association of Rheumatology Health Professionals (ARHP)
San Diego, CA, October 25–26, 2013
Jaskowski TD, Tebo AE—Poster
Nandiwada SL, Jaskowski TD, Mayes M, Satoh M, Tebo AE. Autoantibody diversity in a subset of scleroderma patients with positive ANA and negative for three major disease-specific markers.
Society of Forensic Toxicologists (SOFT)
Orlando, FL, October 28–November 1, 2013
Haglock CJ. Drugs and compounds in forensic toxicology.
Marin SJ. Fundamentals of accurate mass/targeted screening by LC-TOF-MS.
Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC)
Denver, CO, September 10–13, 2013
Tardif KD, Barker A—Poster
Tardif KD, Barker A. Identification of rapidly growing mycobacteria by MALDI-TOF mass spectrometry.
International Congress on Antiphospholipid Antibodies (APLA)
Rio de Janeiro, Brazil, September 18–21, 2013
Willis R, Tebo A, Lakos G, Mahler M, Norman GL, DW Branch, Salmon J, Guerra M, Pierangeli S, Branch DW. Anti-PS/PT (IGG) antibodies correlate with LAC and pregnancy complications in patients with antiphospholipid syndrome.
Tebo A, Jaskowski T—Oral Presentation
Tebo A, Willis R, Jaskowski T, Madger L, Petri M, Pierangeli S, Branch DW. Association of anti-B2glycoprotein I antibodies in a large cohort of lupus patients.
Tebo A, Jaskowski T—Poster
Tebo A, Willis R, Jaskowski T, Salmon J, Petri M, Pierangeli S, Branch DW. Qualitative comparisons of anti-b2glycoprotein I immunoassays in two distinct cohorts of patients.
International Congress of Therapeutic Drug Monitoring & Clinical Toxicology (IATDMCT)
Salt Lake City, UT, September 22–26, 2013
Juenke JM, Johnson-Davis KL—Poster
Juenke JM, Brown PI, Johnson-Davis KL. Application of ultra-high liquid chromatography tandem mass spectrometry to the analysis of three atypical antipsychotics and one antidepressant: risperidone, 9-OH risperidone, aripiprazole ,dehydro-aripiprazole, ziprasidone, venlafaxine, and o-desmethyl-venlafaxine (ODES) in serum and plasma.
Haglock CJ, Strathmann FG—Presentation
Wise P, Haglock CJ, Strathmann FG. Assessment of arsenic toxicity using a combination of quantitative screening and chromatographic separation with inductively coupled plasma-mass spectrometry.
Meyer EJ, Schniedewind B, Boucher R, Johnson-Davis KL, Galinkin JL, Christians U. Cross-validation of Everolimus LC-MS/MS and Thermo Fisher QMS therapeutic drug monitoring assays—the Zortracker cross-validation and TDM support.
Marin SJ, McMillin GA—Poster
Marin SJ, Metcalf A, McMillin GA. Detection of in utero drug exposure using umbilical cord tissue and liquid chromatography time-of-flight mass spectrometry (TOF).
Marin SJ, McMillin GA—Poster
Williams JA, Marin SJ, Chittamma A, Clark C, McMillin GA. Detection of in utero marijuana exposure by three methods using umbilical cord tissue.
Haglock CJ, Strathmann FG—Poster
Haglock CJ, Strathmann FG. Development and validation of a matrix-matched assay to measure iodine in serum by inductively coupled plasma-mass spectrometry.
Marin SJ, McMillin GA—Poster
Lawlor BG, Marin SJ, Chittamma A, Clark CJ, McMillin GA. Development of a qualitative urine drug panel by liquid chromatography time-of-flight mass spectrometry (LC-TOF-MS).
Garrison K, Johnson-Davis KL, Wong SH. Everolimus QMS assay by using Thermofisher Indiko, Beckman DXc, and AU680 analyzers and limited comparison to LC-MS/MS.
Haglock CJ, Strathmann FG—Poster
Parker R, Haglock CJ, Strathmann FG. Mercury amnesia: a simple and robust mercury whole blood assay using inductively coupled plasma mass spectrometry (ICP-MS) without memory effects.
Suh-Lailam BB, Juenke JM, Thompson CD, Johnson-Davis KL—Poster
Suh-Lailam BB, Juenke JM, Thompson CD, Wilson L, Johnson-Davis KL. Performance characteristics of three assays for the therapeutic drug monitoring of methotrexate.
Johnson-Davis KL. Urine drug testing and its role in pain management.
Campbell SC, McMillin G, Sherwin CMT, Spigarelli MG. Utilization of thiopurine methyltransferase pharmacogenomic testing.
11th Workshop on Bioinformatics and 6th Symposium of the Polish Bioinformatics Society
Wraclaw, Poland, September 27–29, 2013
Dittwald P, Valkenborg D, Jürgen Claesen J, Rockwood AL, Gambin A. A few comments on isotopic fine structure.