Animal Reference Pathology

Current Posters and Presentations

Each year, the ARUP Institute for Clinical and Experimental Pathology® presents at more than 200 conferences, workshops, annual meetings, and symposiums for several national and international organizations. Recent posters and presentations include:

JULY 2014

American Association for Clinical Chemistry (AACC)
Chicago, IL, July 27–31, 2014

Grenache DG—Poster
Sowder A, Yarbrough ML, Nerenz R, Mortensen R, Gronowski AM, Grenache DG. An analytical evaluation of the Abbott i-STAT hCG test cartridge.

Perkins S—Presentation
Perkins S. Anemias.

Straseski JA—Presentation
Straseski JA. Banking on the numbers: laboratory assessment of ovarian reserve.

Clark ZD, Frank EF—Poster
Clark ZD, Frank EF. C-ing is believing: enhanced specificity for vitamin C using HPLC with electrochemical detection and automatic alternating column regeneration.

Lyon E— Presentation
Lyon E. Comparing sequencing to high resolution melting in CFTR whole gene analysis.

La'ulu SL, Straseski JA— Poster
La'ulu SL, Straseski JA. Comparison of immunoassays to mass spectrometry for free and total testosterone in men, women and children.

Slev P—Presentation
Slev P. Developments in HIV testing.

Schmidt RL, La'ulu SL, Hanson SE—Poster
Schmidt RL, La'ulu SL, Hanson SE, Rohlfing CL, Little RR. Effects of 49 different rare variants on HbA1c measurements in seven methods.

Grenache DG—Presentation
Grenache DG. Four reasons for a positive hCG test in the absence of pregnancy.

Owen WE, Straseski JA—Poster
Owen WE, Straseski JA. Functional sensitivity of five estradiol immunoassays.

Genzen JR—Presentation
Genzen JR. Fundamentals of critical values: policies, problems and proposed solutions.

Grenache DG—Poster
Suh-Lailam B, Grenache DG. Identifying G6PD deficiency: defining the lower reference limit and evaluating pre-analytical sources of error.

Straseski JA—Presentation
Straseski JA. Interpretation of insulin and C-peptide immunoassay results: using cross reactivity and interferences to your advantage.

Wittwer CT—Presentation
Wittwer CT. Introduction to sequencing and high resolution melting.

Lyon E—Presentation
Lyon E. Molecular pathology coding.

Merrigan SD, Owen WE, Straseski JA—Poster
Merrigan SD, Owen WE, Straseski JA. Performance characteristics of the ARCHITECT Active-B12 (Holotranscobalamin) assay: a marker of vitamin-B12 deficiency.

Wyness SP, Straseski JA—Poster
Wyness SP, Straseski JA. Performance characteristics of six automated 25-hydroxyvitamin D assays: mind your 3’s and 2’s.

Lu J, Grenache DG—Poster
Lu J, Grenache DG. Performance evaluation of the AnshLite myelin basic protein chemiluminescent immunoassay using cerebrospinal fluid.

Erickson JA, Grenache DG—Poster
Erickson JA, Jensen RA, Grenache DG. Performance evaluation of a polyclonal based fecal alpha-1-antitrypsin ELISA.

La'ulu SL, Strathmann FG, Genzen JG—Poster
Scholes KL, La'ulu SL, Ence AT, Logan HL, Parker RL, Strathmann FG, Genzen JG. Performance evaluation of rapid test strips for the identification of EDTA-containing specimens.

Rockwood AL— Presentation
Rockwood AL. Preventative maintenance - the key to sleeping well after implementing.

Liu A, Erali M, Longo N, Pasquali M, De Biase I—Poster
Liu A, Hobert J, Erali M, Pickering J, Longo N, Pasquali M, De Biase I. Quantitative amino acid analysis using liquid chromatography tandem mass spectrometry and aTRAQ reagents. Do we have a new gold standard?

Lu J, Kalp K, Straseski J—Poster
Lu J, Holt C, Choi M, Kalp K, Straseski J. Quantitation of anti-müllerian hormone by the AnshLabs picoAMH ELISA assay.

Grenache DG—Poster
Hackenmueller SA, Grenache DG. Reference intervals for intestinal dissacharidase activity determined from a non-reference population.

Kushnir MM, Rockwood AL, Meikle AW—Poster
Kushnir MM, Rockwood AL, Meikle AW. Serum thyroglobulin measurement in autoantibody positive samples by LC-MS/MS and immunoassay: is positivity rate different between the methods?

Grenache DG—Presentation
Grenache DG. The many faces of hCG.

La'ulu SL, Straseski JA, Genzen JR—Poster
La'ulu SL, Straseski JA, Genzen JR. Thrombin mediated degradation of parathyroid hormone in serum tubes.

Johnson-Davis KL—Presentation
Johnson-Davis KL. Urine drug testing for opiate use and abuse.

JUNE 2014

Canadian Society of Clinical Chemists
Charlottetown, Canada, June 8–11, 2014

McMillin GA—Presentation
McMillin GA. Genetics of therapeutic drug response.

American Society for Mass Spectrometry (ASMS)
Baltimore, MD, June 15–19, 2014

Escobar H, Rockwood AL, Kushnir MM, Meikle AW—Poster
Escobar H, Rockwood AL, Kushnir MM, Meikle AW. Direct measurement of pancreatic polypeptide in human serum and plasma by immunocapture-liquid-chromatography-tandem mass spectrometry.

European Symposium of Biopathology
Paris, France, June 19–21, 2014

South ST—Presentation
South ST. Detection of copy number alterations, ploidy, and loss of heterozygosity across the genome in FFPE specimens: utility for diagnosis and treatment with comparison between FISH-based and as a complement to sequencing assays.

Serbian Diaspora Medical Conference
White Palace, Belgrade, June 19–21, 2014

South ST—Presentation
South ST. Implementing arrays for cytogenetic applications: A discussion of best practices for platform validation, analysis, and interpretation.

Endocrine Society (ENDO)
Chicago, IL, June 21–24, 2014

Lu J, Kalp K, Straseski J—Poster
Lu J, Holt C, Choi M, Kalp K, Straseski J. Analytical evaluation of the AnshLabs anti-müllerian hormone picoAMH ELISA assay.

Kushnir MM, Rockwood AL, Meikle AW—Poster
Kushnir MM, Rockwood AL, Meikle AW. Observational study of data on analysis of thyroglobulin in autoantibody positive samples using commercial immunoassay and LC-MS/MS methods.

Wyness SP, Straseski JA—Poster
Wyness SP, Straseski JA. Performance characteristics of six automated 25-hydroxy vitamin D assays: mind your 3’s and 2’s.

MAY 2014

American Association of Immunologists (AAI) Pittsburgh, PA, May 2–6, 2014

Escobar H, Rockwood AL, Delgado JC—Poster
Zhou Z, Reyes-Vargas E, Escobar H, Rudd B, Rockwood AL, Delgado JC, He X, Jensen PE. Relative resistance to HLA-DM editing is a distinguishing characteristic of type 1 diabetes associated HLA-DQ molecules.

Pediatric Academic Society (PAS)
Vancouver, Canada, May 3–6, 2014

Johnson-Davis KL, McMillin GA—Poster
Campbell SC, Johnson-Davis KL, Linakis MW, Roberts JL, McMillin GA, Sherwin CM, Spigarelli MG. Evaluating the relationship of age and thiopurine methyltransferase activity.

Johnson-Davis KL, McMillin GA—Poster
Linakis MW, Campbell SC, Stockmann C, Johnson-Davis KL, McMillin GA, Sherwin CM, Spigarelli GM. Regional differences in thiopurine methyltransferase activity.

Johnson-Davis KL, McMillin GA—Poster
Campbell SC, Johnson-Davis KL, McMillin GA, Sherwin CM, Spigarelli MG. Trends of pediatric and adolescent TPMT Pharmacogenomic testing.

American Cytogenetics Conference (ACC)
Asheville, NC, May 4–7, 2014

Sederberg M, South S, Toydemir R—Poster
Serrano M, Sederberg M, South S, Toydemir R. Genetic heterogeneity of multi-hit B-cell lymphomas: report of 19 cases.

Paxton CN, Rowe LR, South ST—Presentation
Paxton CN, Rowe LR, South ST. Observations of the genomic landscape beyond 1p19q deletions and EGFR amplification in glioma

American Society of Pediatric Hematology Oncology (ASPHO)
Chicago, IL, May 14–17, 2014

Smock KJ—Poster
Staddon JH, Smock KJ, Schiffman JD, Fluchel MN, Engel ME, Weyrich AS, Campbell RA. Pegasparaginase treatment in pediatric acute lymphoblastic malignancy alters thrombin generation through modulation of the protein C and S system.

American Society for Microbiology (ASM)
Boston, MA, May 17–20, 2014

Couturier B, Elmer H, Schlaberg R—Poster
Couturier B, Weight T, Elmer H, Schlaberg R. Identification of group B streptococcus by three nucleic acid amplification tests (MAX, Illumigene, and GeneOhm) and comparison of 4–8 hour to overnight LIM broth enrichment culture.

Khot PD, Cummings JB, Fisher MA—Poster
Khot PD, Russell K, Cummings JB, Fisher MA. Optimization of sample processing methods to identify bacteria directly from blood cultures by MALDI-TOF mass spectrometry.

Academy of Clinical Laboratory Physicians and Scientists (ACLPS)
San Francisco, CA, May 2–31, 2014

Strathmann FG—Presentation
Hackenmueller SA, Walden J, Yang M, Law C, Strathmann FG. Frequency of overlooked abnormal results in urine and blood identified after retrospective expanded screening for toxic elements by inductively-coupled plasma mass spectrometry highlights limitations with current screening approaches.

Suh-Lailam BB, Rule GS, Johnson-Davis KLP—Poster
Suh-Lailam BB, Rule GS, Johnson-Davis KL. Simultaneous identification of 9 oral antidiabetic drugs in plasma and urine by liquid chromatrography-tandem mass spectrometry.

American Society of Clinical Oncology (ASCO)
Chicago, IL, May 30–Jun 3, 2014

Vaughn C, Samowitz W, Grossman A—Poster
Papanicolau-Sengos A, Hart E, Shen W, Grossmann KF, Vaughn C, Samowitz W, Grossman A. Classification of somatic variants in solid tumors detected by next-generation sequencing (NGS) highlights the need for clinical guidelines.

Bastien RRL, Vaughn CP, Elsberry D, Bernard PS—Poster
Bastien RRL, Vaughn CP, Elsberry D, Stijleman IJ, Bernard PS. Clinical validation of the Prosigna Breast Cancer Prognostic Gene Signature Assay on formalin-fixed paraffin-embedded breast cancer tumors with comparison to standard molecular markers.

Strathmann FG—Presentation
Doyle K, Clark C, Strathmann FG. Improved accuracy of medication compliance determination and significant reduction in turnaround time using a qualitative time-of-flight mass spectrometry and immunoassay-based screening approach.

APRIL 2014

International Society for the Study of Vascular Anomalies (ISSVA)
Melbourne, Australia, April 2–4, 2014

Wooderchak-Donahue WL, Durtschi J, Sumner K, Lewis T, Best H, Bayrak-Toydemir P—Presentation
Wooderchak-Donahue WL, McDonald J, Durtschi J, Sumner K, Lewis T, Stocks J, Stevenson DA, Grimmer JF, Best H, Bayrak-Toydemir P. Clinical utility of a next-generation sequencing panel in the diagnosis of hereditary hemorrhagic telangiectasia (HHT) and other syndromes featuring vascular.

Wooderchak-Donahue WL, Bayrak-Toydemir P—Poster
Wooderchak-Donahue WL, Blei F, Berenstein A, McDonald J, Sorscher M, Bayrak-Toydemir P. Novel RASA1 splice site mutation identified in an infant prenatally diagnosed with cerebral arteriovenous fistula-type (AVF) malformation.

American Association for Cancer Research (AACR)
San Diego, CA, Apr 5–9, 2014

Vaughn CP—Poster
Magdaleno SM, Cheng A, Petraroli R, Sheils O, Tops B, Le Corre D, Kurth H, Blons H, Amato E, Mafficini A, Rachiglio AM, Reimann A, Noppen C, Ainali C, Katayama J, Franco R, Feilotter H, Schageman J, Cree I, Felton A, Costa JL, Rico A, Scarpa A, Machado JC, Nishio K, Normanno N, Ligtenberg M, Vaughn CP, Lacroix L, Laurent-Puig P. The OncoNetwork Consortium: a global collaborative research study on the development and verification of an Ion AmpliSeq RNA gene lung fusion panel.

Thrombosis and Hemostasis Summit of North America (THSNA)
Chicago, IL, April 10–12, 2014

Smock KJ—Poster
Hsu P, Marlar RA, Zantek ND, Smock KJ, Plumhoff E, Meijer P, Van Cott EM. Activated protein C resistance testing: assessment of the quality of testing performed by North American specialized coagulation laboratories.

Smock KJ—Presentation
Smock KJ. Is there a role for laboratory testing for aspirin and clopidogrel effect?

Smock KJ, Heikal NM—Poster
Smock KJ, Plumhoff EA, Meijer P, Hsu P, Zantek ND, Heikal NM, Van Cott EM. Protein S: quality of testing in North American specialized coagulation laboratories.

Smock KJ—Poster
Zantek ND, Hsu P, Meijer P, Plumhoff EA, Refaai MA, Smock KJ, Van Cott EM. Quality of factor XI testing in North American specialized coagulation laboratories.

Smock KJ—Presentation
Smock KJ. Protein S testing update.

Clinical Immunology Society (CIS)
Baltimore, MD, April 10–13, 2014

Coonrod EM, Durtschi J, Hill HR, Voelkerding KV, Kumanovics A—Poster
Coonrod EM, Durtschi J, Hill HR, Voelkerding KV, Kumanovics A. Performance of next-generation-sequencing-based gene panels for primary immunodeficiencies.

Pan American Society for Clinical Virology (PASCV)
Daytona, FL , April 25–30, 2014

Mallory MA, Hymas W, Hillyard DR—Poster
Mallory MA, Hymas W, Lopez L, Hillyard DR. Evaluation of the Chemagic MSM I automated extraction platform for viral nucleic acid recovery.

Pyne MT, Hillyard DR—Poster
Pyne MT, Hillyard DR. Evaluation of the Roche CAP/CTM HCV Test, v2.0.

Tardif KD, Schlaberg R—Poster
Tardif KD, Prichard M, Schlaberg R. Simultaneous titration and antiviral drug susceptibility testing for HSV1 and 2.

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