Dr. Grenache Discusses pre-natal testing with mlo
The September 2009 MLO magazine cover story focuses on pre-, neo-, and post-natal testing. MLO invited David G. Grenache, PhD, medical director of the Special Chemistry Laboratory at ARUP, to answer questions regarding the topic of his AACC 2009 presentation in Chicago. In the interview, "Scientists Seeking Answers for Fetuses and Infants," Dr. Grenache discussed the importance of fetal-lung maturity testing.
- When I was a post-doctoral fellow in clinical chemistry the laboratory called to tell me they had accidently centrifuged an amniotic fluid specimen that had been submitted to the lab for a fetal lung-maturity (FLM) test. As these specimens are not to be centrifuged prior to analysis, the specimen was clearly compromised but, being that it was amniotic fluid, it was not easily re-collected. I began to wonder what effect centrifugation and resuspension had on the result of the FLM test, so I set about doing a series of investigations that examined not only the centrifugation effect but also other preanalytical factors that might affect the test.
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(MLO. “Scientists Seeking Answers for Fetuses and Infants .” September 2009.